While not actually difficult, it is easily one of the most frustrating games I've played in a very long time.
You are 'Dr. Stiles' and basically you follow a rather cheesy storyline and preform surgery's pertaining to that line. Besides the fact that I killed the first person I operated on, ended up calling the nurse a 'vindictive bitch' more than once, and nearly killed myself while saving someone else, it's not that bad of a game.
The downfall (for me anyway) is the fact that it requires at least some measure of coordination and speed. You choose from several different surgical instruments to preform a certain task, and it's mindnumbingly easy to accidentally touch something else.
I'm still trying to save a patient from multiple aneurysms.